Publications

Kleinboelting S, Ramos-Espiritu L, Buck H, Colis L, van den Heuvel J, J Glickman F, Levin LR, Buck J, Steegborn C.  2016.  Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site.. J Biol Chem. 291(18):9776-84.

Ramos-Espiritu L, Kleinboelting S, Navarrete FA, Alvau A, Visconti PE, Valsecchi F, Starkov A, Manfredi G, Buck H, Adura C et al..  2016.  Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.. Nat Chem Biol. 12(10):838-44.

Ramos-Espiritu L, Diaz A, Nardin C, Saviola AJ, Shaw F, Plitt T, Yang X, Wolchok J, Pirog EC, Desman G et al..  2016.  The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.. Oncotarget. 7(29):45597-45607.

Rahman N, Ramos-Espiritu L, Milner TA, Buck J, Levin LR.  2016.  Soluble adenylyl cyclase is essential for proper lysosomal acidification.. J Gen Physiol. 148(4):325-39.

Bitterman JL, Ramos-Espiritu L, Diaz A, Levin LR, Buck J.  2013.  Pharmacological distinction between soluble and transmembrane adenylyl cyclases.. J Pharmacol Exp Ther. 347(3):589-98.