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LevBuck Laboratory

Publications

Found 35 results
2020
Hidalgo DM, Romarowski A, Gervasi MG, Navarrete F, Balbach M, Salicioni AM, Levin LR, Buck J, Visconti PE.  2020.  Capacitation increases glucose consumption in murine sperm.. Mol Reprod Dev.
Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J et al..  2020.  Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.. Cell Metab. 31(5):969-986.e7.
Balbach M, Gervasi MGracia, Hidalgo DMartin, Visconti PE, Levin LR, Buck J.  2020.  Metabolic changes in mouse sperm during capacitation†.. Biol Reprod. 103(4):791-801.
Balbach M, Fushimi M, Huggins DJ, Steegborn C, Meinke PT, Levin LR, Buck J.  2020.  Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public-private drug discovery institute collaboration†.. Biol Reprod. 103(2):176-182.
Balbach M, Buck J, Levin LR.  2020.  Using an Extracellular Flux Analyzer to Measure Changes in Glycolysis and Oxidative Phosphorylation during Mouse Sperm Capacitation.. J Vis Exp. (155)
2019
Navarrete FA, Aguila L, Martin-Hidalgo D, Tourzani DA, Luque GM, Ardestani G, Garcia-Vazquez FA, Levin LR, Buck J, Darszon A et al..  2019.  Transient Sperm Starvation Improves the Outcome of Assisted Reproductive Technologies.. Front Cell Dev Biol. 7:262.
2018
Zhou D, Ota K, Nardin C, Feldman M, Widman A, Wind O, Simon A, Reilly M, Levin LR, Buck J et al..  2018.  Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.. Sci Signal. 11(555)
Wiggins SV, Steegborn C, Levin LR, Buck J.  2018.  Pharmacological modulation of the CO/HCO/pH-, calcium-, and ATP-sensing soluble adenylyl cyclase.. Pharmacol Ther. 190:173-186.
2017
Gandhi JK, Chowdhury URoy, Manzar Z, Buck J, Levin LR, Fautsch MP, Marmorstein AD.  2017.  Differential Intraocular Pressure Measurements by Tonometry and Direct Cannulation After Treatment with Soluble Adenylyl Cyclase Inhibitors.. J Ocul Pharmacol Ther. 33(8):574-581.
Valsecchi F, Konrad C, D'Aurelio M, Ramos-Espiritu LS, Stepanova A, Burstein SR, Galkin A, Magranè J, Starkov A, Buck J et al..  2017.  Distinct intracellular sAC-cAMP domains regulate ER Ca signaling and OXPHOS function.. J Cell Sci. 130(21):3713-3727.
2016
Kleinboelting S, Ramos-Espiritu L, Buck H, Colis L, van den Heuvel J, J Glickman F, Levin LR, Buck J, Steegborn C.  2016.  Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site.. J Biol Chem. 291(18):9776-84.
Ramos-Espiritu L, Kleinboelting S, Navarrete FA, Alvau A, Visconti PE, Valsecchi F, Starkov A, Manfredi G, Buck H, Adura C et al..  2016.  Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.. Nat Chem Biol. 12(10):838-44.
Ramos-Espiritu L, Diaz A, Nardin C, Saviola AJ, Shaw F, Plitt T, Yang X, Wolchok J, Pirog EC, Desman G et al..  2016.  The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.. Oncotarget. 7(29):45597-45607.
Rahman N, Ramos-Espiritu L, Milner TA, Buck J, Levin LR.  2016.  Soluble adenylyl cyclase is essential for proper lysosomal acidification.. J Gen Physiol. 148(4):325-39.
Navarrete FA, Alvau A, Lee HChang, Levin LR, Buck J, De Leon PMartin-, Santi CM, Krapf D, Mager J, Fissore RA et al..  2016.  Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models.. Sci Rep. 6:33589.
2015
Watson RL, Buck J, Levin LR, Winger RC, Wang J, Arase H, Muller WA.  2015.  Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.. J Exp Med. 212(7):1021-41.
Levin LR, Buck J.  2015.  Physiological roles of acid-base sensors.. Annu Rev Physiol. 77:347-62.
2014
Kleinboelting S, Diaz A, Moniot S, van den Heuvel J, Weyand M, Levin LR, Buck J, Steegborn C.  2014.  Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate.. Proc Natl Acad Sci U S A. 111(10):3727-32.
Hess KC, Liu J, Manfredi G, Mühlschlegel FA, Buck J, Levin LR, Barrientos A.  2014.  A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity.. FASEB J. 28(10):4369-80.
Shahidullah M, Mandal A, Wei G, Levin LR, Buck J, Delamere NA.  2014.  Nonpigmented ciliary epithelial cells respond to acetazolamide by a soluble adenylyl cyclase mechanism.. Invest Ophthalmol Vis Sci. 55(1):187-97.
Buck J, Levin LR.  2014.  The role of soluble adenylyl cyclase in health and disease.. Biochim Biophys Acta. 1842(12 Pt B):2533-4.
Chen X, Baumlin N, Buck J, Levin LR, Fregien N, Salathe M.  2014.  A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in soluble adenylyl cyclase knockout mice.. Am J Respir Cell Mol Biol. 51(6):750-60.
Martinez J, Stessin AM, Campana A, Hou J, Nikulina E, Buck J, Levin LR, Filbin MT.  2014.  Soluble adenylyl cyclase is necessary and sufficient to overcome the block of axonal growth by myelin-associated factors.. J Neurosci. 34(28):9281-9.
2013
Valsecchi F, Ramos-Espiritu LS, Buck J, Levin LR, Manfredi G.  2013.  cAMP and mitochondria.. Physiology (Bethesda). 28(3):199-209.
Zippin JH, Chen Y, Straub SG, Hess KC, Diaz A, Lee D, Tso P, Holz GG, Sharp GWG, Levin LR et al..  2013.  CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor.. J Biol Chem. 288(46):33283-91.