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Lab Team

Primary Investigator

Headshot of Jochen  Buck
Jochen Buck , M.D., Ph.D.
  • Professor of Pharmacology
Headshot of Lonny Levin
Lonny R. Levin , Ph.D.
  • Professor of Pharmacology

Lab Members

Headshot of Shakarr  Wiggins
Shakarr Wiggins
  • Neuroscience Graduate Student
Research Focus:

I am in the Neuroscience program at Weill Cornell. Currently, I am using mouse models to understand the regulation of intraocular pressure. In addition, I have studied other potential therapeutic roles of sAC and cAMP within sperm.

  • Wesleyan College
Headshot of Melanie Balbach
Melanie Balbach
  • Postdoctoral Associate in Pharmacology
Research Focus:

With my research I’m trying to understand the changes in energy metabolism during sperm capacitation and how the soluble adenylate cyclase regulates these processes. In parallel, I work on developing a soluble adenylate cyclase inhibitor into an on-demand, reversible male contraceptive. For this project I recently got awarded with a fellowship by the Male Contraceptive Initiative.

  • University of Bayreuth (Germany)
  • Bonn International Graduate School Life & Medical Sciences
  • Caesar Institute
jacob ferreira
Jacob Ferreira
  • Pharmacology PhD Graduate Student
Research Focus:

My project is to purify and elucidate the function of an endogenous inhibitor to soluble adenylyl cyclase (sAC). As a potential small molecule, this endogenous inhibitor is present in cell lysate and is capable of fully inhibiting sAC activity. My long-term goals are to combine the mechanism-based drug knowledge I gained in Pharmacy School with the research expertise I will gain in Grad School to developing new & more effective drugs that produce fewer side effects.

  • University of Connecticut
Lubna Ghanem
  • Research Technician I
Anna Gorovyy
Anna Gorovyy
  • Research Technician I
Research Focus:

While studying at Hunter I joined Dr. Kleiman laboratory where I researched effects of HuR protein on cancer cell growth and survival. I joined Dr. Buck and Dr. Levin laboratory and am very excited to do immunology research using dendritic cell and to analyze response of second messenger cAMP to inhibitors.

Headshot of Stephanie Jackvony
Stephanie Jackvony
  • Neuroscience PhD Graduate Student
Research Focus:

My project focuses on the role of soluble adenylyl cyclase in microglia, specifically in mechanisms of activation.  I am passionate about neuroimmunology, especially in the context of aging and neurodegenerative disease, and my work in the Levin/Buck lab allows me to explore these concepts from a basic science lens.  Discoveries from this project could potentially uncover useful therapeutic targets for treating age-related diseases.

  • Connecticut College
Navpreet Kaur
  • Research Technician I
Headshot of Thomas Rossetti
Thomas Rossetti
  • Pharmacology PhD Graduate Student
Research Focus:

My overall research goal in the lab is to discover and characterize pharmacological and novel endogenous activators of soluble adenylyl cyclase (sAC). In pursuit of this goal, I am currently using a high-throughput screening method designed to identify small-molecule activators of sAC.

  • Brandeis University
Headshot of Oluwatoni Sonubi
Oluwatoni Sonubi
  • Research Technician I
Research Focus:

I was interested in the male contraceptive project currently running in the lab. My interest lay in human behavior and I hope to obtain a PhD in neuroscience sometime in the immediate future. I also have an interest in promoting sciences within minorities, especially amongst black males, as I believe this is a domain of all research that can be improved upon.

  • CUNY Hunter College

Weill Cornell Medicine LevBuck Laboratory 1300 York Avenue, E505 New York, NY 10065 Phone: (212) 746-6752