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Lab Team

Primary Investigator

Headshot of Jochen  Buck
Jochen Buck , M.D., Ph.D.
  • Professor of Pharmacology
Headshot of Lonny Levin
Lonny R. Levin , Ph.D.
  • Professor of Pharmacology

Lab Members

Headshot of Sylvia  Ayoub
Sylvia Ayoub
  • Research Technician I
Research Focus:

In my time in the LevBuck lab, I have assisted post-docs in their research on sperm motility and contributed to the efforts of the male contraceptive initiative. Currently, I am working on the phenotypic characterizations of the ADCY10 C2 KO mouse model. 

  • State University of New York at Albany
Hayden Belliveau
  • Research Technician I
  • University of Connecticut
Headshot of Jacob Ferreira
Jacob Ferreira , Pharm.D.
  • Pharmacology PhD Graduate Student
Research Focus:

My project is to purify and elucidate the function of an endogenous inhibitor to soluble adenylyl cyclase (sAC). As a potential small molecule, this endogenous inhibitor is present in cell lysate and is capable of fully inhibiting sAC activity. My long-term goals are to combine the mechanism-based drug knowledge I gained in Pharmacy School with the research expertise I will gain in Grad School to developing new & more effective drugs that produce fewer side effects.

  • University of Connecticut
Headshot of Samuel  Nidorf
Samuel Nidorf
  • Research Technician I
  • Skidmore College
Headshot of Carla  Ritagliati
Carla Ritagliati , Ph.D.
  • Instructor in Pharmacology
Research Focus:

My overall research goal is to better understand the molecular events leading to acquisition of fertilization competence in mammalian sperm, which could lead to development of male contraceptives and/or diagnostic and therapeutic approaches for male infertility. My project focuses on the regulation of capacitation by post-translational modifications such as lysine acetylation and sAC-dependent PKA phosphorylation.

Headshot of Natalia  Rivera Sanchez
Natalia Rivera Sanchez
  • Pharmacology PhD Graduate Student
Research Focus:

My main research goal is to use a mouse model to study the localization and distribution of soluble adenylyl cyclase (sAC) in sperm cells and somatic tissues as well as understanding isoform diversity and possible binding partners of this protein. 

In addition, I'm working in studying the safety and toxicity of sAC inhibitors and assisting in testing such inhibitors in mammalian animal models. For this project, I was awarded a fellowship from the Male Contraceptive Initiative (MCI). 

  • University of Puerto Rico in Cayey
Headshot of Thomas Rossetti
Thomas Rossetti
  • Postdoctoral Associate in Pharmacology
Research Focus:

My overall research goal in the lab is to discover and characterize pharmacological and novel endogenous activators of soluble adenylyl cyclase (sAC). In pursuit of this goal, I am currently using a high-throughput screening method designed to identify small-molecule activators of sAC.

  • Brandeis University

Weill Cornell Medicine LevBuck Laboratory 1300 York Avenue, E505 New York, NY 10065 Phone: (212) 746-6752