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Found 42 results
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Title
Type
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R
Rahman N
,
Ramos-Espiritu L
,
Milner TA
,
Buck J
,
Levin LR
. 2016.
Soluble adenylyl cyclase is essential for proper lysosomal acidification.
.
J Gen Physiol. 148(4):325-39.
Rahman N
,
Buck J
,
Levin LR
. 2013.
pH sensing via bicarbonate-regulated "soluble" adenylyl cyclase (sAC).
.
Front Physiol. 4:343.
Ramos-Espiritu L
,
Diaz A
,
Nardin C
,
Saviola AJ
,
Shaw F
,
Plitt T
,
Yang X
,
Wolchok J
,
Pirog EC
,
Desman G
et al.
. 2016.
The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.
.
Oncotarget. 7(29):45597-45607.
Ramos-Espiritu L
,
Kleinboelting S
,
Navarrete FA
,
Alvau A
,
Visconti PE
,
Valsecchi F
,
Starkov A
,
Manfredi G
,
Buck H
,
Adura C
et al.
. 2016.
Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.
.
Nat Chem Biol. 12(10):838-44.
Rossetti T
,
Jackvony S
,
Buck J
,
Levin LR
. 2021.
Bicarbonate, carbon dioxide and pH sensing via mammalian bicarbonate-regulated soluble adenylyl cyclase.
.
Interface Focus. 11(2):20200034.
Rossetti T
,
Ferreira J
,
Ghanem L
,
Buck H
,
Steegborn C
,
Myers RW
,
Meinke PT
,
Levin LR
,
Buck J
. 2022.
Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential.
.
Front Physiol. 13:1013845.
S
Salazar E
,
Bank EM
,
Ramsey N
,
Hess KC
,
Deitsch KW
,
Levin LR
,
Buck J
. 2012.
Characterization of Plasmodium falciparum adenylyl cyclase-β and its role in erythrocytic stage parasites.
.
PLoS One. 7(6):e39769.
Shahidullah M
,
Mandal A
,
Wei G
,
Levin LR
,
Buck J
,
Delamere NA
. 2014.
Nonpigmented ciliary epithelial cells respond to acetazolamide by a soluble adenylyl cyclase mechanism.
.
Invest Ophthalmol Vis Sci. 55(1):187-97.
T
Topal H
,
Fulcher NB
,
Bitterman J
,
Salazar E
,
Buck J
,
Levin LR
,
Cann MJ
,
Wolfgang MC
,
Steegborn C
. 2012.
Crystal structure and regulation mechanisms of the CyaB adenylyl cyclase from the human pathogen Pseudomonas aeruginosa.
.
J Mol Biol. 416(2):271-86.
V
Valsecchi F
,
Konrad C
,
D'Aurelio M
,
Ramos-Espiritu LS
,
Stepanova A
,
Burstein SR
,
Galkin A
,
Magranè J
,
Starkov A
,
Buck J
et al.
. 2017.
Distinct intracellular sAC-cAMP domains regulate ER Ca signaling and OXPHOS function.
.
J Cell Sci. 130(21):3713-3727.
Valsecchi F
,
Ramos-Espiritu LS
,
Buck J
,
Levin LR
,
Manfredi G
. 2013.
cAMP and mitochondria.
.
Physiology (Bethesda). 28(3):199-209.
W
Wang X
,
Cai B
,
Yang X
,
Sonubi OO
,
Zheng Z
,
Ramakrishnan R
,
Shi H
,
Valenti L
,
Pajvani UB
,
Sandhu J
et al.
. 2020.
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.
.
Cell Metab. 31(5):969-986.e7.
Watson RL
,
Buck J
,
Levin LR
,
Winger RC
,
Wang J
,
Arase H
,
Muller WA
. 2015.
Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
.
J Exp Med. 212(7):1021-41.
Wertheimer E
,
Krapf D
,
de la Vega-Beltran JL
,
Sánchez-Cárdenas C
,
Navarrete F
,
Haddad D
,
Escoffier J
,
Salicioni AM
,
Levin LR
,
Buck J
et al.
. 2013.
Compartmentalization of distinct cAMP signaling pathways in mammalian sperm.
.
J Biol Chem. 288(49):35307-20.
Wiggins SV
,
Steegborn C
,
Levin LR
,
Buck J
. 2018.
Pharmacological modulation of the CO/HCO/pH-, calcium-, and ATP-sensing soluble adenylyl cyclase.
.
Pharmacol Ther. 190:173-186.
Z
Zhou D
,
Ota K
,
Nardin C
,
Feldman M
,
Widman A
,
Wind O
,
Simon A
,
Reilly M
,
Levin LR
,
Buck J
et al.
. 2018.
Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.
.
Sci Signal. 11(555)
Zippin JH
,
Chen Y
,
Straub SG
,
Hess KC
,
Diaz A
,
Lee D
,
Tso P
,
Holz GG
,
Sharp GWG
,
Levin LR
et al.
. 2013.
CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor.
.
J Biol Chem. 288(46):33283-91.
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